Search Results
Overview
| Uniprot ID | A0A8I5Y1V4 |
|---|---|
| Protein Name | Prefoldin subunit 5 |
| Gene Name | Pfdn5 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 42 | QLKVVQTKYVEAKDC |
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC
Protein Sequence
10
MAQSINITEL
20
NLPQLEMLKN
30
QLDQEVEFLS
40
TSIAQLKVVQ
50
TKYVEAKDCL
60
NVFPLTLASQ
70
MYVPGKLHDV
80
EHVLIDVGTG
90
YYVEKTAEDA
100
KDFFKRKIDF
110
LTKQMEKIQP
120
ALQEKHAMKQ
130
AVVEMMSQKI
140
QQLTALGATQ
ATAKA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016272 | prefoldin complex |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0006457 | protein folding |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.