Search Results
Overview
| Uniprot ID | A0A8I5Y1W8 |
|---|---|
| Protein Name | Leucine-rich repeat-containing protein 59 |
| Gene Name | Lrrc59 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 55 | KLDLSKNKLQQLPAD |
Function
Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores
Protein Sequence
10
MSCPAFPPYC
20
FQRPVLIAAL
30
PKATVLDLSC
40
NKLSTLPSDF
50
CGLTHLVKLD
60
LSKNKLQQLP
70
ADFGRLVNLQ
80
HLDLLNNRLV
90
TLPVSFAQLK
100
NLKWLDLKDN
110
PLDPVLAKVA
120
GDCLDEKQCK
130
QCANKVLQHM
140
KAVQADQERE
150
RQRRLEVERE
160
AEKKREAKQQ
170
AKEAKERELR
180
KREKAEEKER
190
RRKEYDAQKA
200
SKREQEKKPK
210
KETNQAPKSK
220
SGSRPRKPPP
230
RKHNRSWAVL
240
KGLLLLLLLC
250
VAGGLVVCRV
260
TGLQQQPLCT
270
SVNAIYDNAV
280
QGLRHHEILQ
WVLQTDSQQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0005635 | nuclear envelope |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.