Search Results
Overview
| Uniprot ID | A0A8I5Y917 |
|---|---|
| Protein Name | Transcription initiation factor IIF subunit alpha |
| Gene Name | Gtf2f1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 366 | TLRAAASKLEQGKRT |
Function
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation
Protein Sequence
10
MCVVRVNTAK
20
RYNIMAFNAA
30
DKVNFATWNQ
40
ARLERDLSNK
50
KIYQEEEMPE
60
SGAGSEFNRK
70
LREEARRKKY
80
GIVLKEFRPE
90
DQPWLLRVNG
100
KSGRKFKGIK
110
KGGVTENTAY
120
YIFTQCADGA
130
FEAFPVQNWY
140
NFTPLARHRT
150
LTAEEAEEEW
160
ERRNKVLNHF
170
SIMQQRRLKD
180
QDQDEDEEEK
190
EKRSRKKPSE
200
LRIHDLEDDL
210
EMSSDASDAS
220
GEEGSRASKA
230
KKKAPVTKAG
240
RKKKKKKGSD
250
DEAFEDSDDG
260
DFEGQEVDYM
270
SDGSSSSPDE
280
AEGKPKVPQQ
290
EDGPKGVDEQ
300
SESSEESEEE
310
KPPEEDKEEE
320
EEKKCPPLPL
330
NPPKKKTPPK
340
RERKPSGGSS
350
KGTSRPGTPS
360
AEAASTSSTL
370
RAAASKLEQG
380
KRTSETPAAK
390
RLRMDTGPQS
400
LSGKSTPSSG
410
DVQVTEDAVR
420
RYLTRKPMTT
430
KDLLKKFQTK
440
KTGLSSEQTV
450
NVLAQILKRL
460
NPERKMIGDK
MHFSLKE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Biological Process | GO:0032968 | positive regulation of transcription elongation by RNA polymerase II |
| Biological Process | GO:0006367 | transcription initiation at RNA polymerase II promoter |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.