Search Results
Overview
| Uniprot ID | A0A8I5Y9T5 |
|---|---|
| Protein Name | Syntaxin-1B |
| Gene Name | Stx1b |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 103 | AAPNPDEKTKQELED |
| 105 | PNPDEKTKQELEDLT |
| 116 | EDLTADIKKTANKVR |
| 159 | QHSTLSRKFVEVMTE |
| 222 | KMDSQMTKQALNEIE |
| 237 | TRHNEIIKLETSIRE |
| 79 | EIRGCIEKLSEDVEQ |
| 88 | SEDVEQVKKQHSAIL |
| 89 | EDVEQVKKQHSAILA |
Function
Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm
Protein Sequence
10
MSDKLDMAEI
20
EKFDKSKLKK
30
TGTQEKSPLP
40
SKETIEQEKQ
50
AGNEAKDSDD
60
EEEVVHVDRD
70
HFMDEFFEQV
80
EEIRGCIEKL
90
SEDVEQVKKQ
100
HSAILAAPNP
110
DEKTKQELED
120
LTADIKKTAN
130
KVRSKLKAIE
140
QSIEQEEGLN
150
RSSADLRIRK
160
TQHSTLSRKF
170
VEVMTEYNAT
180
QSKYRDRCKD
190
RIQRQLEITG
200
RTTTNEELED
210
MLESGKLAIF
220
TDDIKMDSQM
230
TKQALNEIET
240
RHNEIIKLET
250
SIRELHDMFV
260
DMAMLVESQG
270
EMIDRIEYNV
280
EHSVDYVERA
290
VSDTKKAVKY
300
QSKARRKKIM
310
IIICCVVLGV
320
VLASSIGGTL
GL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0031594 | neuromuscular junction |
| Cellular Component | GO:0048787 | presynaptic active zone membrane |
| Molecular Function | GO:0003785 | actin monomer binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0005102 | signaling receptor binding |
| Molecular Function | GO:0005484 | SNAP receptor activity |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:1903422 | negative regulation of synaptic vesicle recycling |
| Biological Process | GO:2000463 | positive regulation of excitatory postsynaptic potential |
| Biological Process | GO:1904050 | positive regulation of spontaneous neurotransmitter secretion |
| Biological Process | GO:0010468 | regulation of gene expression |
| Biological Process | GO:0010807 | regulation of synaptic vesicle priming |
| Biological Process | GO:0061669 | spontaneous neurotransmitter secretion |
| Biological Process | GO:0016081 | synaptic vesicle docking |
| Biological Process | GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.