Search Results

Overview

Uniprot IDA0A8I5YBQ9
Protein NamecAMP-dependent protein kinase catalytic subunit alpha
Gene NamePrkaca
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
50 LDHFDRIKTLGTGSF

Function

No function data available.

Protein Sequence

10 MLASECCRRL 20 GGVCLKGMKE 30 FLAKAKEDFL 40 KKWETPSQNT 50 AQLDHFDRIK 60 TLGTGSFGRV 70 MLVKHKESGN 80 HYAMKILDKQ 90 KVVKLKQIEH 100 TLNEKRILQA 110 VNFPFLVKLE 120 FSFKDNSNLY 130 MVMEYVPGGE 140 MFSHLRRIGR 150 FSEPHARFYA 160 AQIVLTFEYL 170 HSLDLIYRDL 180 KPENLLIDQQ 190 GYIQVTDFGF 200 AKRVKGRTWT 210 LCGTPEYLAP 220 EIILSKGYNK 230 AVDWWALGVL 240 IYEMAAGYPP 250 FFADQPIQIY 260 EKIVSGKVRF 270 PSHFSSDLKD 280 LLRNLLQVDL 290 TKRFGNLKNG 300 VNDIKNHKWF 310 ATTDWIAIYQ 320 RKVEAPFIPK 330 FKGPGDTSNF 340 DDYEEEEIRV 350 SINEKCGKEF TEF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0001669 acrosomal vesicle
Cellular Component GO:0005930 axoneme
Cellular Component GO:0005952 cAMP-dependent protein kinase complex
Cellular Component GO:0005813 centrosome
Cellular Component GO:0036126 sperm flagellum
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0004691 cAMP-dependent protein kinase activity
Molecular Function GO:0140198 histone H1-4S35 kinase activity
Molecular Function GO:0000287 magnesium ion binding
Molecular Function GO:0030145 manganese ion binding
Molecular Function GO:0019904 protein domain specific binding
Molecular Function GO:0034237 protein kinase A regulatory subunit binding
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0106310 protein serine kinase activity
Molecular Function GO:0004712 protein serine/threonine/tyrosine kinase activity
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0071377 cellular response to glucagon stimulus
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0030007 intracellular potassium ion homeostasis
Biological Process GO:0006397 mRNA processing
Biological Process GO:1904539 negative regulation of glycolytic process through fructose-6-phosphate
Biological Process GO:0051447 negative regulation of meiotic cell cycle
Biological Process GO:0120186 negative regulation of protein localization to chromatin
Biological Process GO:1904262 negative regulation of TORC1 signaling
Biological Process GO:0045542 positive regulation of cholesterol biosynthetic process
Biological Process GO:0045722 positive regulation of gluconeogenesis
Biological Process GO:0050766 positive regulation of phagocytosis
Biological Process GO:0010898 positive regulation of triglyceride catabolic process
Biological Process GO:0099170 postsynaptic modulation of chemical synaptic transmission
Biological Process GO:2000810 regulation of bicellular tight junction assembly
Biological Process GO:0070507 regulation of microtubule cytoskeleton organization
Biological Process GO:0045667 regulation of osteoblast differentiation
Biological Process GO:0061136 regulation of proteasomal protein catabolic process
Biological Process GO:0048240 sperm capacitation
Cellular Component GO:0097546 ciliary base
Cellular Component GO:0005829 cytosol
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0005811 lipid droplet
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0031594 neuromuscular junction
Cellular Component GO:0016607 nuclear speck
Cellular Component GO:0048471 perinuclear region of cytoplasm
Cellular Component GO:0044853 plasma membrane raft
Cellular Component GO:0098794 postsynapse

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.