Search Results

Overview

Uniprot IDA0A8I5ZK55
Protein NameNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
Gene NameNdufs4
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
196 KVPKPKSKSYGANFS

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MRGRTLVSRK 20 APMEPRVLGS 30 PGSAAAGEGL 40 CGGAVNRTVA 50 PEKGRSLGDF 60 SPNVLASLPF 70 VTCLPHSSLK 80 GLLNTSTWKL 90 ADGQTRDTQL 100 ITVDEKLDVT 110 PLTGVPEEHI 120 KTRKVRIFVP 130 ARNNMQSGVN 140 NTKKWKMEFD 150 TRERWENPLM 160 GWASTADPLS 170 NMVLTFSAKE 180 DAVAFAEKHG 190 WSYDVEGRKV 200 PKPKSKSYGA 210 NFSWNKRTRV STK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0045271 respiratory chain complex I
Molecular Function GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process GO:0007420 brain development
Biological Process GO:0032981 mitochondrial respiratory chain complex I assembly
Biological Process GO:0072593 reactive oxygen species metabolic process
Biological Process GO:0022904 respiratory electron transport chain
Biological Process GO:0051591 response to cAMP

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.