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Overview

Uniprot ID	A0A8I5ZPF2
Protein Name	Sarcolemmal membrane-associated protein
Gene Name	Slmap
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
63	ALVWFDHKTSKFYLQ

Function

Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion

Protein Sequence

10 MPSALAIFTC 20 RPNSHPFQER 30 HVYLDEPIKI 40 GRSVARCRPA 50 QNNATFDCKV 60 LSRNHALVWF 70 DHKTSKFYLQ 80 DTKSSNGTFI 90 NSQRLSRGSE 100 ESPPCEILSG 110 DIIQFGVDVT 120 ENTRKVTHGC 130 IVSTIKLFLP 140 DGMEARLRSD 150 VIHAPLPSPV 160 DKVAANTPSM 170 YSQELFQLSQ 180 YLQEALHREQ 190 MLEQKLATLQ 200 RLLAITQEAS 210 DTSWQALIDE 220 DRLLSRLEVM 230 GNQLQACSKN 240 QTEDSLRKEL 250 VALQEDKHSY 260 ETTAKESLRR 270 VLQEKIEVVR 280 KLSEVERSLS 290 NTEDECTHLR 300 EMNERTQEEL 310 RELANKYNGA 320 VNEIKDLSDK 330 LKAAEGKQEE 340 IQQKGQAEKK 350 ELQAKIDDME 360 EKEQELQAKI 370 EALQADNDFT 380 NERLTALQVR 390 LEPLQEKTLK 400 ECSSLERLLS 410 KSGGDCTFIH 420 QFIECQKKLM 430 VQGHLTKVVE 440 ESKLSKENQA 450 KAKESDLSDT 460 LSPSKEKSSD 470 DTTDAQMDEQ 480 DLNEPLAKVS 490 LLKDDLQGTQ 500 AETEAKQDTQ 510 HLRKELVEAQ 520 ELARASKQKC 530 FDLQALLEEE 540 RKAYRNQVEE 550 SAKQIQVLQV 560 QLQRLHMDME 570 NLQEEKDTEI 580 SSTRDKLLSA 590 QDEILLLHQA 600 AAKAVSERDT 610 DFMSLQEELK 620 KVRAELEGWR 630 KAASEYEEEI 640 RSLQSTFQLR 650 CQQCEVQQRE 660 EATRLQGELE 670 KLKKEWDVLE 680 NECRSLKKEN 690 VLLSSELQRQ 700 EKELHNSQKQ 710 SLELTSDLSI 720 LQMTRKELEN 730 QMGSLKEQHL 740 RDEADLKTLL 750 SKAENQAKDV 760 QKEYEKTQTV 770 LSELKLKFEM 780 TEQEKQSITD 790 ELKQCKDNLK 800 LLREKGNNKP 810 WPWMPMVAAL 820 VAVTAMVLYV PGLARASP

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005813	centrosome
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Cellular Component	GO:0031966	mitochondrial membrane
Cellular Component	GO:0042383	sarcolemma

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.