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Overview

Uniprot IDA0A8I5ZS15
Protein NameSeptin
Gene NameSeptin2
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
174 FMKAIHNKVNIVPVI

Function

Filament-forming cytoskeletal GTPase

Protein Sequence

10 MSKQQPTQFI 20 NPETPGYVGF 30 ANLPNQVHRK 40 SVKKGFEFTL 50 MVVGESGLGK 60 STLINSLFLT 70 DLYPERIIPG 80 AAEKIERTVQ 90 IEASTVEIEE 100 RGVKLRLTVV 110 DTPGYGDAIN 120 SRDCFKTIIS 130 YIDEQFERYL 140 HDESGLNRRH 150 IIDNRVHCCF 160 YFISPFGHGL 170 KPLDVAFMKA 180 IHNKVNIVPV 190 IAKADTLTLK 200 ERERLKKRIL 210 DEIEEHSIKI 220 YHLPDAESDE 230 DEDFKEQTRL 240 LKASIPFSVV 250 GSNQLIEAKG 260 KKVRGRLYPW 270 GVVEVENPEH 280 NDFLKLRTML 290 ITHMQDLQEV 300 TQDLHYENFR 310 SERLKRGGRL 320 KVENEDMNKD 330 QILLEKEAEL 340 RRMQEMIARM 350 QAQMQMQMQG 360 GDTDSSTLGH HV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0045202 synapse
Molecular Function GO:0030234 enzyme regulator activity
Molecular Function GO:0005525 GTP binding
Biological Process GO:0051301 cell division
Biological Process GO:0060271 cilium assembly
Biological Process GO:0007010 cytoskeleton organization
Biological Process GO:0007224 smoothened signaling pathway
Cellular Component GO:0005930 axoneme
Cellular Component GO:0009986 cell surface
Cellular Component GO:0060170 ciliary membrane
Cellular Component GO:0032154 cleavage furrow
Cellular Component GO:0045171 intercellular bridge
Cellular Component GO:0030496 midbody
Cellular Component GO:0005634 nucleus
Cellular Component GO:0032391 photoreceptor connecting cilium
Cellular Component GO:0031105 septin complex
Cellular Component GO:0097227 sperm annulus
Cellular Component GO:0005819 spindle

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.