Search Results
Overview
| Uniprot ID | A0A8I5ZSG1 |
|---|---|
| Protein Name | C-terminal-binding protein 1 |
| Gene Name | Ctbp1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 269 | KALAQALKEGRIRGA |
Function
Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation
Protein Sequence
10
MSGVRPPIMN
20
GPMHPRPLVA
30
LLDGRDCTVE
40
MPILKDVATV
50
AFCDAQSTQE
60
IHEKVLNEAV
70
GALMYHTITL
80
TREDLEKFKA
90
LRIIVRIGSG
100
FDNIDIKSAG
110
DLGIAVCNVP
120
AASVEETADS
130
TLCHILNLYR
140
RTTWLHQALR
150
EGTRVQSVEQ
160
IREVASGAAR
170
IRGETLGIIG
180
LGRVGQAVAL
190
RAKAFGFNVL
200
FYDPYLSDGI
210
ERALGLQRVS
220
TLQDLLFHSD
230
CVTLHCGLNE
240
HNHHLINDFT
250
VKQMRQGAFL
260
VNTARGGLVD
270
EKALAQALKE
280
GRIRGAALDV
290
HESEPFSFSQ
300
GPLKDAPNLI
310
CTPHAAWYSE
320
QASIEMREEA
330
AREIRRAITG
340
RIPDSLKNCV
350
NKDHLTAATH
360
WASMDPAVVH
370
PELNGAAYRY
380
PPGVVSVAPT
390
GIPAAVEGIV
400
PSAMSLSHGL
410
PPVAHPPHAP
420
SPGQTVKPEA
DRDHTTDQL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0051287 | NAD binding |
| Molecular Function | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| Molecular Function | GO:0003714 | transcription corepressor activity |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.