Search Results
Overview
| Uniprot ID | A0A8I5ZW65 |
|---|---|
| Protein Name | Splicing factor 45 |
| Gene Name | Rbm17 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 41 | KAALTQAKSQRTKQS |
Function
Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites
Protein Sequence
10
MSLYDDLGVE
20
TSDSKTEGWS
30
KNFKLLQSQL
40
QVKKAALTQA
50
KSQRTKQSTV
60
LAPVIDLKRG
70
GSSDDRQIVD
80
TPPHVAAGLK
90
DPVPSGFSAG
100
EVLIPLADEY
110
DPMFPNDYEK
120
VVKRQREERQ
130
RQRELERQKE
140
IEEREKRRKD
150
RHEASGFSRR
160
PDPDSDEDED
170
YERERRKRSM
180
GGAAIAPPTS
190
LVEKDKELPR
200
DFPYEEDSRP
210
RSQSSKAAIP
220
PPVYEEPDRP
230
RSPTGPSNSF
240
LANMGGTVAH
250
KIMQKYGFRE
260
GQGLGKHEQG
270
LSTALSVEKT
280
SKRGGKIIVG
290
DATEKGESQD
300
ASKKSDSNPL
310
TEILKCPTKV
320
VLLRNMVGAG
330
EVDEDLEVET
340
KEECEKYGKV
350
GKCVIFEIPV
360
LTNCHFVCLP
370
AVVDLNGRYF
380
GGRVVKACFY
390
NLDKFRVLDL
AEQV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0045292 | mRNA cis splicing, via spliceosome |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.