Search Results
Overview
| Uniprot ID | A0A8I5ZWK0 |
|---|---|
| Protein Name | Developmentally-regulated GTP-binding protein 2 |
| Gene Name | Drg2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 46 | AQLLEPSKSASSKGE |
| 51 | PSKSASSKGEGFDVM |
Function
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation
Protein Sequence
10
MGILEKISEI
20
EKEIARTQKN
30
KATEYHLGLL
40
KAKLAKYRAQ
50
LLEPSKSASS
60
KGEGFDVMKS
70
GDARVALIGF
80
PSVGKSTFLS
90
LMTSTASEAA
100
SYEFTTLTCI
110
PGVIEYKGAN
120
IQLLDLPGII
130
EGAAQGRGRG
140
RQVIAVARTA
150
DVVVMMLDAT
160
KGDVQRSLLE
170
KELESVGIRL
180
NKHKPNIYFK
190
PKKGGGISFN
200
STVTLTQCSE
210
KLVQLILHEY
220
KIFNAEVLFR
230
EDCSPDDFID
240
VIVGNRVYMP
250
CLYVYNKIDQ
260
ISMEEVDRLA
270
RKPNSVVISC
280
GMKLNLDYLL
290
EMLWEYLALT
300
CIYTKKRGQR
310
PDFTDAIILR
320
KGASVEHVCH
330
RIHRSLASQF
340
KYALVWGTST
350
KYSPQRVGLT
360
HTMEHEDVIQ
IVKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0003723 | RNA binding |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.