Search Results
Overview
| Uniprot ID | A0A8I5ZYY8 |
|---|---|
| Protein Name | Eukaryotic translation initiation factor 4H |
| Gene Name | Eif4h |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 163 | SVRLVRDKDTDKFKG |
| 167 | VRDKDTDKFKGFCYV |
| 210 | AEGRKQDKGGFGFRK |
| 217 | KGGFGFRKGGPDDRG |
Function
Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA
Protein Sequence
10
MGLGGQSVRA
20
ALRGLAAPPR
30
GPQSAPGPAA
40
GPVGPRPGAA
50
ARACVRAICD
60
QAARRTAPVA
70
GREGGGGVIL
80
RGPSSLARWF
90
LKERRRQMAD
100
FDTYDDRAYS
110
SFGGGRGSRG
120
SAGGHGSRSQ
130
KELPTEPPYT
140
AYVGNLPFNT
150
VQGDIDAIFK
160
DLSIRSVRLV
170
RDKDTDKFKG
180
FCYVEFDEVD
190
SLKEALTYDG
200
ALLGDRSLRV
210
DIAEGRKQDK
220
GGFGFRKGGP
230
DDRGYRDDFL
240
GGRGGSRPGD
250
RRAGPPMGSR
260
FRDGPPLRGS
270
NMDFREPTEE
280
ERAQRPRLQL
290
KPRTVATPLN
300
QVANPNSAIF
310
GGARPREEVV
QKEQE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003743 | translation initiation factor activity |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.