Search Results

Overview

Uniprot ID	A0A8I5ZZT1
Protein Name	-
Gene Name	Rap1gap2
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
730	NLKFRFDKLSHASSS

Function

GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state

Protein Sequence

10 MSQPAGRMHC 20 RKAGIRAAVV 30 LIGLLHKSRK 40 QNKEKRKQEL 50 ANSSDVTLPD 60 RPLSPPLTAP 70 PTMKSAEFFE 80 MLEKMQGIKL 90 EEQRPGPQKN 100 KEDYIPYPSI 110 EEVVEKGGPY 120 PQIILPQFGG 130 YWIEDPENVG 140 TPTSLGSSVY 150 EEEEEDSLSP 160 NTFGYKLECR 170 GEARAYRRHF 180 LGKDHLNFYC 190 TGSSLGNLIL 200 SIKCEEAEGI 210 EYLRIILRSK 220 LKTVHERIPL 230 AGLSKLPSVP 240 QIAKAFCDDA 250 VGLKFNPVLY 260 PKASQMIVSY 270 DEHDVNNTFK 280 FGVIYQKARQ 290 TLEEELFGNN 300 EESPAFKEFL 310 DLLGDTITLQ 320 DFKGFRGGLD 330 VTHGQTGVES 340 VYTTFRDREI 350 MFHVSTKLPF 360 TDGDTQQLQR 370 KRHIGNDIVA 380 IIFQEENTPF 390 VPDMIASNFL 400 HAYIVVQAES 410 TGTETPSYKV 420 SVTAREDVPA 430 FGPPLPSPPV 440 FQKGTEFREF 450 LLTKLTNAEN 460 ACCKSDKFAK 470 LEDRTRAALL 480 DNLHDELHTH 490 TQVMLGMGPE 500 EDKFENGGHG 510 GFLESFKRAI 520 RVRSHSMETM 530 VGSQRKLHGG 540 NIPGSLSGGI 550 VHNSMEVTKT 560 TFSPPVAAAT 570 VKNQSRSPIK 580 RRSGLFPRLH 590 SGSEGQGDSR 600 TRCDSASSTP 610 KTPDGGHSSQ 620 EIKSETSSNP 630 SSPEICPNKE 640 KPFIKLKENG 650 RANISRSSSS 660 TSSFSSTAGE 670 GEAMEECDSG 680 SSQPSTTSPF 690 KQEVFVYSPS 700 PSSESPSLGA 710 AATPIIMSRS 720 PTDAKSRNSP 730 RSNLKFRFDK 740 LSHASSSAGH

Gene Ontology

Classification	GO ID	Description
Molecular Function	GO:0005096	GTPase activator activity
Biological Process	GO:0051056	regulation of small GTPase mediated signal transduction

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.