Search Results
Overview
| Uniprot ID | A0A8I6A0J2 |
|---|---|
| Protein Name | Branched-chain-amino-acid aminotransferase |
| Gene Name | Bcat1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 289 | PKFVRSWKGGTGDFK |
Function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine
Protein Sequence
10
MLQRLRSSLR
20
RVPAGGSPII
30
PLSPAPPNCN
40
PGLSAAPLCH
50
AFPRARSFVM
60
AYLSRATATL
70
ARQDCSNGCS
80
ASYAEEEELE
90
ASTESYDEEG
100
GSEASTQTFR
110
AKDLIITKAD
120
VLKKKPDPSS
130
LVFGASFTDH
140
MLMVEWTSKY
150
GWDKPHIKPF
160
ENLSIHPAAS
170
VLHYAVELFE
180
GLKAFRGVDN
190
KIRLFRPDLN
200
MKRMCRSAVR
210
TTLPEFDKEE
220
LLQCVLQLIQ
230
LDREWVPYST
240
SASLYIRPTF
250
IGIEPSLGVK
260
KPSKALLFVI
270
LSPVGSYFSN
280
GTFSPVSLWA
290
NPKFVRSWKG
300
GTGDFKMGCN
310
YGSSLLAQCE
320
AAENGCHQVL
330
WLYGKENRIT
340
EVGTMNLFLY
350
WINKDGEEEL
360
ATPPLDGVIL
370
PGVTRQSILE
380
LGEEWGEFKV
390
CERHITMDDL
400
STALEENRVK
410
EMFGSGTACV
420
VCPVASILYK
430
GQMLHIPTME
440
NGHKLSSRIM
450
AKLTDIQYGR
460
IKSEWTLELP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0052656 | L-isoleucine-2-oxoglutarate transaminase activity |
| Molecular Function | GO:0052654 | L-leucine-2-oxoglutarate transaminase activity |
| Molecular Function | GO:0052655 | L-valine-2-oxoglutarate transaminase activity |
| Biological Process | GO:0008652 | amino acid biosynthetic process |
| Biological Process | GO:0009082 | branched-chain amino acid biosynthetic process |
| Biological Process | GO:0006629 | lipid metabolic process |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.