Search Results
Overview
| Uniprot ID | A0A8I6A0V2 |
|---|---|
| Protein Name | Ras-related protein Rab-42 |
| Gene Name | Rab42 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 63 | LPAGLRVKLQLWDTA |
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The physiological function of RAB42 remains undefined
Protein Sequence
10
MEAAGCSYQF
20
RIALLGDAAV
30
GKTSLLRCYV
40
AGARGAAELD
50
PEPTVGVEFY
60
SRALRLPAGL
70
RVKLQLWDTA
80
GQERFRCITR
90
SFYRNMVGVL
100
LVFDVTNRES
110
FEHIQAWHQE
120
VISTHGSDKV
130
IFLLVGHKCD
140
LSTRCVSTQE
150
AEELAASLGM
160
AFVETSAKSN
170
CNVDLAFDTV
180
TSAIEQALQQ
190
GDIKLEEDWA
200
GVRLLHRAPN
210
PRSSSRKQDS
GPCQC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Molecular Function | GO:0003925 | G protein activity |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0016192 | vesicle-mediated transport |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.