Search Results
Overview
| Uniprot ID | A0A8I6A1J3 |
|---|---|
| Protein Name | Dual specificity mitogen-activated protein kinase kinase 1 |
| Gene Name | Map2k1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | NLEALQKKLEELELD |
| 35 | LEAFLTQKQKVGELK |
| 66 | VVFKVSHKPSGLVMA |
| 75 | SGLVMARKLIHLEIK |
| 82 | KLIHLEIKPAIRNQI |
Function
No function data available.
Protein Sequence
10
MKLERTNLEA
20
LQKKLEELEL
30
DEQQRKRLEA
40
FLTQKQKVGE
50
LKDDDFEKIS
60
ELGAGNGGVV
70
FKVSHKPSGL
80
VMARKLIHLE
90
IKPAIRNQII
100
RELQVLHECN
110
SPYIVGFYGA
120
FYSDGEISIC
130
MEHMDGGSLD
140
QVLKKAGRIP
150
EQILGKVSIA
160
VIKGLTYLRE
170
KHKIMHRDVK
180
PSNILVNSRG
190
EIKLCDFGVS
200
GQLIDSMANS
210
FVGTRSYMSP
220
ERLQGTHYSV
230
QSDIWSMGLS
240
LVEMAVGRYP
250
IPPPDAKELE
260
LLFGCQVEGD
270
AAETPPRPRT
280
PGRPLSSYGM
290
DSRPPMAIFE
300
LLDYIVNEPP
310
PKLPSGVFSL
320
EFQDFVNKCL
330
IKNPAERADL
340
KQLMVHAFIK
350
RSDAEEVDFA
360
GWLCSTIGLN
370
QPSTPTHAAS
I
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005938 | cell cortex |
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005769 | early endosome |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005770 | late endosome |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0004708 | MAP kinase kinase activity |
| Molecular Function | GO:0004674 | protein serine/threonine kinase activity |
| Molecular Function | GO:0004713 | protein tyrosine kinase activity |
| Biological Process | GO:0010629 | negative regulation of gene expression |
| Biological Process | GO:2000641 | regulation of early endosome to late endosome transport |
| Biological Process | GO:0090170 | regulation of Golgi inheritance |
| Biological Process | GO:0032872 | regulation of stress-activated MAPK cascade |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.