Search Results
Overview
| Uniprot ID | A0A8I6A2C1 |
|---|---|
| Protein Name | Small nuclear ribonucleoprotein G |
| Gene Name | LOC120100604 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 3 | *****MSKAHPPELK |
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing
Protein Sequence
10
MSKAHPPELK
20
KFMDKKLSLK
30
LNGTRRVQGI
40
LRGFDPFTNL
50
VIDECVEMVT
60
SGQQNNIGTV
70
VIRGNSIIML
ETLERV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0043186 | P granule |
| Cellular Component | GO:0071011 | precatalytic spliceosome |
| Cellular Component | GO:0034719 | SMN-Sm protein complex |
| Cellular Component | GO:0097526 | spliceosomal tri-snRNP complex |
| Cellular Component | GO:0005685 | U1 snRNP |
| Cellular Component | GO:0005689 | U12-type spliceosomal complex |
| Cellular Component | GO:0005686 | U2 snRNP |
| Cellular Component | GO:0071004 | U2-type prespliceosome |
| Cellular Component | GO:0005687 | U4 snRNP |
| Cellular Component | GO:0005682 | U5 snRNP |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0000387 | spliceosomal snRNP assembly |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.