Search Results
Overview
| Uniprot ID | A0A8I6A493 |
|---|---|
| Protein Name | 1-phosphatidylinositol-5-phosphate 4-kinase |
| Gene Name | Pip4k2b |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 32 | KKHFVCQKVKLFRAS |
Function
No function data available.
Protein Sequence
10
MSSNCTSTTA
20
VAVAPLSASK
30
TKTKKKHFVC
40
QKVKLFRASE
50
PILSVLMWGV
60
NHTINELSNV
70
PVPVMLMPDD
80
FKAYSKIKVD
90
NHLFNKENLP
100
SRFKFKEYCP
110
MVFRNLRERF
120
GIDDQDYQNS
130
VTRSAPINSD
140
SQGRCGTRFL
150
TTYDRRFVIK
160
TVSSEDVAEM
170
HNILKKYHQF
180
IVECHGNTLL
190
PQFLGMYRLT
200
VDGVETYMVV
210
TRNVFSHRLT
220
VHRKYDLKGS
230
TVAREASDKE
240
KAKDLPTFKD
250
NDFLNEGQKL
260
RVGEESKKNF
270
LEKLKRDVEF
280
LAQLKIMDYS
290
LLVGIHDVDR
300
AEQEETEVED
310
RAEEEECEND
320
GVGGGLLCSY
330
GTPPDSPGNL
340
LSFPRFFGPG
350
EFDPSVDVYA
360
MKSHESAPKK
370
EVYFMAIIDI
380
LTPYDAKKKA
390
AHAAKTVKHG
400
ARNLKATESG
410
GAVHCKWALV
RRFCRRPQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005776 | autophagosome |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:1902635 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process |
| Biological Process | GO:0061909 | autophagosome-lysosome fusion |
| Biological Process | GO:0046627 | negative regulation of insulin receptor signaling pathway |
| Biological Process | GO:2000786 | positive regulation of autophagosome assembly |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.