Search Results
Overview
| Uniprot ID | A0A8I6A7V6 |
|---|---|
| Protein Name | Tyrosine-protein phosphatase non-receptor type substrate 1 |
| Gene Name | Sirpa |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 138 | YYCVKFQKGIVEPDT |
| 425 | FRLHEPEKNAREITQ |
Function
No function data available.
Protein Sequence
10
MQRPRRVLLP
20
GWLPLACSAC
30
SLIEPSTTSE
40
SWLPSFSPGA
50
SGKELKVTQA
60
DKSVSVAAGD
70
SATLNCTVSS
80
LTPVGPIKWF
90
KGEGQNRSPI
100
YSFIGGEHFP
110
RITNVSDATK
120
RNNMDFSICI
130
SNVTPEDAGT
140
YYCVKFQKGI
150
VEPDTEIKSG
160
GGTTLYVLAK
170
PSSPEVSGPD
180
SRGSPGQTVN
190
FTCKSYGFSP
200
RNITLKWLKD
210
GKELSHLETT
220
ISSKSNVSYN
230
ISSTVSVKLS
240
PEDIHSRVIC
250
EVAHVTLEGR
260
PLNGTANFSN
270
IIRVSPTLKI
280
TQQPLTPASQ
290
VNLTCQVQKF
300
YPKALQLNWL
310
ENGNLSRTDK
320
PEHFTDNRDG
330
TYNYTSLFLV
340
NSSAHREDVV
350
FTCQVEHDSQ
360
PAITENHTVR
370
AFAHSSSGGS
380
METIPDNNAY
390
YNWNVFIGVG
400
VACALLVVLL
410
MAALYLLRIK
420
QKKVSFHFRL
430
HEPEKNAREI
440
TQIQDTNDIN
450
DITYADLNLP
460
KEKKPAPRVP
470
EPNNHTEYAS
480
IETGKLPRPE
490
DTLTYADLDM
500
VHLNRAQPTP
510
KPEPSFSEYA
SVQVQRK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0019903 | protein phosphatase binding |
| Molecular Function | GO:0017124 | SH3 domain binding |
| Biological Process | GO:0097529 | myeloid leukocyte migration |
| Biological Process | GO:0050765 | negative regulation of phagocytosis |
| Biological Process | GO:0032675 | regulation of interleukin-6 production |
| Biological Process | GO:0045428 | regulation of nitric oxide biosynthetic process |
| Biological Process | GO:0032680 | regulation of tumor necrosis factor production |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.