Search Results

Overview

Uniprot IDA0A8I6AAD3
Protein NameSerine/threonine-protein phosphatase
Gene NamePpp3cb
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
172 LTEYFTFKQECKIKY
332 NNKAAVLKYENNVMN
56 IPRVDVLKNHLVKEG
61 VLKNHLVKEGRVDEE

Function

No function data available.

Protein Sequence

10 MAAPEPARAA 20 PPPPPPPPPP 30 LGADRVVKAV 40 PFPPTHRLTS 50 EEVFDMDGIP 60 RVDVLKNHLV 70 KEGRVDEEIA 80 LRIINEGAAI 90 LRREKTMIEV 100 EAPITVCGDI 110 HGQFFDLMKL 120 FEVGGSPANT 130 RYLFLGDYVD 140 RGYFSIECVL 150 YLWVLKILYP 160 STLFLLRGNH 170 ECRHLTEYFT 180 FKQECKIKYS 190 ERVYEACMEA 200 FDSLPLAALL 210 NQQFLCVHGG 220 LSPEIHTLDD 230 IRRLDRFKEP 240 PAFGPMCDLL 250 WSDPSEDFGN 260 EKSQEHFSHN 270 TVRGCSYFYN 280 YPAVCEFLQN 290 NNLLSIIRAH 300 EAQDAGYRMY 310 RKSQTTGFPS 320 LITIFSAPNY 330 LDVYNNKAAV 340 LKYENNVMNI 350 RQFNCSPHPY 360 WLPNFMDVFT 370 WSLPFVGEKV 380 TEMLVNVLSI 390 CSDDELMTEG 400 EDQFDVGSAA 410 ARKEIIRNKI 420 RAIGKMARVF 430 SVLREESESV 440 LTLKGLTPTG 450 MLPSGVLAGG 460 RQTLQSAIRG 470 FSPPHRICSF 480 EEAKGLDRIN 490 ERMPPRKDAV 500 QQDGFNSLNT 510 AHTTENHGTG NHSAQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005955 calcineurin complex
Cellular Component GO:0005829 cytosol
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0030315 T-tubule
Cellular Component GO:0030018 Z disc
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0005516 calmodulin binding
Molecular Function GO:0033192 calmodulin-dependent protein phosphatase activity
Molecular Function GO:0046983 protein dimerization activity
Molecular Function GO:0030346 protein phosphatase 2B binding
Biological Process GO:0033173 calcineurin-NFAT signaling cascade
Biological Process GO:0017156 calcium-ion regulated exocytosis
Biological Process GO:0023057 negative regulation of signaling
Biological Process GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:1905673 positive regulation of lysosome organization
Biological Process GO:1900182 positive regulation of protein localization to nucleus
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:1900242 regulation of synaptic vesicle endocytosis
Biological Process GO:0048741 skeletal muscle fiber development

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.