Search Results
Overview
| Uniprot ID | A0A8I6ACY4 |
|---|---|
| Protein Name | 40S ribosomal protein S12 |
| Gene Name | Rps12l4 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 118 | DREGKPRKVVGCSCV |
Function
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Subunit of the 40S ribosomal complex
Protein Sequence
10
MRPPAAFSPA
20
AAKFRGGGSS
30
GIAAGGVMDV
40
NTALQEVLKT
50
ALIHDGLARG
60
IREAAKALDK
70
RQAHLCVLAS
80
NCDEPMYVKL
90
VEALCAEHQI
100
NLIKVDDNKK
110
LGEWVGLCKI
120
DREGKPRKVV
130
GCSCVVVKDY
140
GKESQAKDVI
EEYFKCKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0005840 | ribosome |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Biological Process | GO:0006412 | translation |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.