Search Results
Overview
| Uniprot ID | A0A8I6AG46 |
|---|---|
| Protein Name | mRNA cap guanine-N(7) methyltransferase |
| Gene Name | Rnmt |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 109 | GLTERKRKLQPQDAL |
Function
Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC
Protein Sequence
10
MESSVKASVD
20
SETESSPGVN
30
ETAAASGQRL
40
SEKTRQQADQ
50
PKTQDDLVEQ
60
NSSYVQDSPS
70
KKRKLDVEII
80
LDEKHSEDDG
90
GASKRSKLER
100
GGGSEDEPSP
110
GGLTERKRKL
120
QPQDALETQT
130
RKFQKLEEGH
140
SSAVAAHYNE
150
LQEVGLVKRS
160
QSRIFYLRNF
170
NNWIKSILIG
180
EILEKVRQRK
190
NRDITVLDLG
200
CGKGGDLLKW
210
RKGRISRLVC
220
ADIADISMKQ
230
CQQRYEDMKC
240
RRDNEYIFSA
250
EFITADCSKE
260
LLVEKFHDPE
270
MYFDICSCQF
280
ACHYSFESLE
290
QADMMLRNAC
300
GRLNPGGYFI
310
GTTPNSFELI
320
RRLEASETES
330
FGNEIYTVKF
340
QKKGNYPLFG
350
CKYDFNLEGV
360
VDVPEFLVYF
370
PLLTEMAKKY
380
NMKLIYKKTF
390
LEFYEEKIKN
400
NENKMLLKRM
410
QALESYPANE
420
NSKLASEKAG
430
DYAHAAEYMK
440
NSQGTLSKSE
450
WEATSIYLVF
AFEKQQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004482 | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| Molecular Function | GO:0003723 | RNA binding |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.