Search Results
Overview
| Uniprot ID | A0A8I6AMP1 |
|---|---|
| Protein Name | V-type proton ATPase subunit |
| Gene Name | Atp6v0d1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 113 | IDDKLKEKMVVEFRH |
| 336 | RFFEHEVKLNKLAFL |
| 358 | FYAFVKLKEQECRNI |
| 379 | IAQRHRAKIDNYIPI |
Function
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment
Protein Sequence
10
MSFFPELYFN
20
VDNGYLEGLV
30
RGLKAGVLSQ
40
ADYLNLVQCE
50
TLEGFLCAAP
60
AVLELVLWIR
70
LALNSQKSSC
80
LCPATARIKD
90
LKLHLQSTDY
100
GNFLANEASP
110
LTVSVIDDKL
120
KEKMVVEFRH
130
MRNHAYEPLA
140
SFLDFITYSY
150
MIDNVILLIT
160
GTLHQRSIAE
170
LVPKCHPLGS
180
FEQMEAVNIA
190
QTPAELYNAI
200
LVDTPLAAFF
210
QDCISEQDLD
220
EMNIEIIRNT
230
LYKAYLESFY
240
KFCTLLGGTT
250
ADAMCPILEF
260
EADRRAFIIT
270
INSFGTELSK
280
EDRAKLFPHC
290
GRLYPEGLAQ
300
LARADDYEQV
310
KNVADYYPEY
320
KLLFEGAGSN
330
PGDKTLEDRF
340
FEHEVKLNKL
350
AFLNQFHFGV
360
FYAFVKLKEQ
370
ECRNIVWIAE
380
CIAQRHRAKI
DNYIPIF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0033179 | proton-transporting V-type ATPase, V0 domain |
| Molecular Function | GO:0046961 | proton-transporting ATPase activity, rotational mechanism |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.