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Overview

Uniprot IDA0A8I6AMZ5
Protein Name-
Gene NameSnrpa1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
176 KRGAQLAKDIARRSK
183 KDIARRSKTFNPGAG
195 GAGLPTDKKKGGPSA

Function

Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA

Protein Sequence

10 MKALSQITVQ 20 YSYYFQDFSF 30 ILIFVVFFPS 40 TGYKIPVIEN 50 LGATLDQFDA 60 IDFSDNEIRK 70 LDGFPLLRRL 80 KTLLVNNNRI 90 CRIGEGLDQA 100 LPCLTELILT 110 NNSLVELGDL 120 DPLASLKSLT 130 YLSILRNPVT 140 NKKHYRLYVI 150 YKVPQVRVLD 160 FQKVKLKERQ 170 EAEKMFKGKR 180 GAQLAKDIAR 190 RSKTFNPGAG 200 LPTDKKKGGP 210 SAGDVEAIKN 220 AIANASTLAE 230 VERLKGLLQS 240 GQIPGRERRS 250 GPSDEGEEEM EDGTVTNGS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016607 nuclear speck
Cellular Component GO:0005686 U2 snRNP
Cellular Component GO:0071007 U2-type catalytic step 2 spliceosome
Cellular Component GO:0071005 U2-type precatalytic spliceosome
Molecular Function GO:0030620 U2 snRNA binding
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0007283 spermatogenesis

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.