Search Results
Overview
| Uniprot ID | A0A8I6ANE0 |
|---|---|
| Protein Name | Dihydropyrimidinase-related protein 2 |
| Gene Name | Dpysl2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 105 | EIRRASGKEALQNIY |
| 29 | NLGSGSPKPRQKFCG |
| 359 | YVTKVMSKSAAEVIA |
| 371 | VIAQARKKGTVVYGE |
| 469 | RMSVIWDKAVVTGKM |
| 524 | SVKTISAKTHNSALE |
| 573 | SGRYIPRKPFPDFVY |
| 581 | PFPDFVYKRIKARSR |
| 621 | VTPASSAKTSPAKQQ |
| 626 | SAKTSPAKQQAPPVR |
| 9 | AERKQSGKAAEDEEV |
Function
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis
Protein Sequence
10
MAERKQSGKA
20
AEDEEVPAFF
30
KNLGSGSPKP
40
RQKFCGMFCP
50
VEGSSENKTI
60
DFDSLSVGRG
70
SGQVVAQQRD
80
VAHLGPDPHR
90
QSRRASGEPS
100
VESGRKVEIR
110
RASGKEALQN
120
IYDQSDRLLI
130
KGGKIVNDDQ
140
SFYADIYMED
150
GLIKQIGENL
160
IVPGGVKTIE
170
AHSRMVIPGG
180
IDVHTRFQMP
190
DQGMTSADDF
200
FQGTKAALAG
210
GTTMIIDHVV
220
PEPGTSLLAA
230
FDQWREWADS
240
KSCCDYSLHV
250
DITEWHKGIQ
260
EEMEALVKDH
270
GVNSFLVYMA
280
FKDRFQLTDS
290
QIYEVLSVIR
300
DIGAIAQVHA
310
ENGDIIAEEQ
320
QRILDLGITG
330
PEGHVLSRPE
340
EVEAEAVNRS
350
ITIANQTNCP
360
LYVTKVMSKS
370
AAEVIAQARK
380
KGTVVYGEPI
390
TASLGTDGSH
400
YWSKNWAKAA
410
AFVTSPPLSP
420
DPTTPDFLNS
430
LLSCGDLQVT
440
GSAHCTFNTA
450
QKAVGKDNFT
460
LIPEGTNGTE
470
ERMSVIWDKA
480
VVTGKMDENQ
490
FVAVTSTNAA
500
KVFNLYPRKG
510
RISVGSDADL
520
VIWDPDSVKT
530
ISAKTHNSAL
540
EYNIFEGMEC
550
RGSPLVVISQ
560
GKIVLEDGTL
570
HVTEGSGRYI
580
PRKPFPDFVY
590
KRIKARSRLA
600
ELRGVPRGLY
610
DGPVCEVSVT
620
PKTVTPASSA
630
KTSPAKQQAP
640
PVRNLHQSGF
650
SLSGAQIDDN
660
IPRRTTQRIV
670
APPGGRANIT
SLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0045171 | intercellular bridge |
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0098685 | Schaffer collateral - CA1 synapse |
| Molecular Function | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| Molecular Function | GO:0019901 | protein kinase binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0007010 | cytoskeleton organization |
| Biological Process | GO:0007399 | nervous system development |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.