Search Results
Overview
| Uniprot ID | A0A8I6AP08 |
|---|---|
| Protein Name | Vesicle-fusing ATPase |
| Gene Name | Nsf |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 254 | IVEQMGCKHVKGILL |
| 702 | TTIAQQVKGKKVWIG |
Function
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin
Protein Sequence
10
MGRPMLKTMQ
20
AARCPTDELS
30
LSNCAVVNEK
40
DYQSGQHVMV
50
RTSPNHKYIF
60
TLRTHPSVVP
70
GCIAFSLPQR
80
KWAGLSIGQD
90
IEVALYSFDK
100
AKQCIGTMTI
110
EIDFLQKKNI
120
DSNPYDTDKM
130
AAEFIQQFNN
140
QAFSVGQQLV
150
FSFNDKLFGL
160
LVKDIEAMDP
170
SILKGEPASG
180
KRQKIEVGLV
190
VGNSQVAFEK
200
AENSSLNLIG
210
KAKTKENRQS
220
IINPDWNFEK
230
MGIGGLDKEF
240
SDIFRRAFAS
250
RVFPPEIVEQ
260
MGCKHVKGIL
270
LYGPPGCGKT
280
LLARQIGKML
290
NAREPKVVNG
300
PEILNKYVGE
310
SEANIRKLFA
320
DAEEEQRRLG
330
ANSGLHIIIF
340
DEIDAICKQR
350
GSMAGSTGVH
360
DTVVNQLLSK
370
IDGVEQLNNI
380
LVIGMTNRPD
390
LIDEALLRPG
400
RLEVKMEIGL
410
PDEKGRLQIL
420
HIHTARMRGH
430
QLLSADVDIK
440
ELAVETKNFS
450
GAELEGLVRA
460
AQSTAMNRHI
470
KASTKVEVDM
480
EKAESLQVTR
490
GDFLASLEND
500
IKPAFGTNQE
510
DYASYIMNGI
520
IKWGDPVTRV
530
LDDGELLVQQ
540
TKNSDRTPLV
550
SVLLEGPPHS
560
GKTALAAKIA
570
EESNFPFIKI
580
CSPDKMIGFS
590
ETAKCQAMKK
600
IFDDAYKSQL
610
SCVVVDDIER
620
LLDYVPIGPR
630
FSNLVLQALL
640
VLLKKAPPQG
650
RKLLIIGTTS
660
RKDVLQEMEM
670
LNAFSTTIHV
680
PNIATGEQLL
690
EALELLGNFK
700
DKERTTIAQQ
710
VKGKKVWIGI
720
KKLLMLIEMS
730
LQMDPEYRVR
740
KFLALMREEG
ASPLDFD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0035255 | ionotropic glutamate receptor binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0030165 | PDZ domain binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Molecular Function | GO:0017075 | syntaxin-1 binding |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:0045732 | positive regulation of protein catabolic process |
| Biological Process | GO:0001921 | positive regulation of receptor recycling |
| Biological Process | GO:0035494 | SNARE complex disassembly |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.