Search Results
Overview
| Uniprot ID | A0A8I6AP17 |
|---|---|
| Protein Name | Protein FAM162A |
| Gene Name | Fam162a |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 56 | RHRVPLHKPTDFEKK |
Function
Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly
Protein Sequence
10
EWASGHCFRL
20
CERNVSSPLR
30
LTRNTDLKRI
40
NGFCTKPQES
50
PKAPTQSYRH
60
RVPLHKPTDF
70
EKKILLWSGR
80
FKKEEEIPET
90
ISFEMLDAAK
100
NKIRVKVSYL
110
MIALTVAGCV
120
YMVIEGKKAA
130
KRHESLTSLN
140
LERKARLREE
AAMKAKAD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.