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Overview

Uniprot ID	A0A8I6AWK8
Protein Name	Sarcolemmal membrane-associated protein
Gene Name	Slmap
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
63	ALVWFDHKTSKFYLQ

Function

Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion

Protein Sequence

10 MPSALAIFTC 20 RPNSHPFQER 30 HVYLDEPIKI 40 GRSVARCRPA 50 QNNATFDCKV 60 LSRNHALVWF 70 DHKTSKFYLQ 80 DTKSSNGTFI 90 NSQRLSRGSE 100 ESPPCEILSG 110 DIIQFGVDVT 120 ENTRKVTHGC 130 IVSTIKLFLP 140 DGMEARLRSD 150 VIHAPLPSPV 160 DKVAANTPSM 170 YSQELFQLSQ 180 YLQEALHREQ 190 MLEQKLATLQ 200 RLLAITQEAS 210 DTSWQALIDE 220 DRLLSRLEVM 230 GNQLQACSKN 240 QTEDSLRKEL 250 VALQEDKHSY 260 ETTAKESLRR 270 VLQEKIEVVR 280 KLSEVERSLS 290 NTEDECTHLR 300 EMNERTQEEL 310 RELANKYNGA 320 VNEIKDLSDK 330 LKAAEGKQEE 340 IQQKGQAEKK 350 ELQAKIDDME 360 EKEQELQAKI 370 EALQADNDFT 380 NERLTALQEK 390 LMVQGHLTKV 400 VEESKLSKEN 410 QAKAKESDLS 420 DTLSPSKEKS 430 SDDTTDAQMD 440 EQDLNEPLAK 450 VSLLKDDLQG 460 TQAETEAKQD 470 TQHLRKELVE 480 AQELARASKQ 490 KCFDLQALLE 500 EERKAYRNQV 510 EESAKQIQVL 520 QVQLQRLHMD 530 MENLQEEKDT 540 EISSTRDKLL 550 SAQDEILLLH 560 QAAAKAVSER 570 DTDFMSLQEE 580 LKKVRAELEG 590 WRKAASEYEE 600 EIRSLQSTFQ 610 LRCQQCEVQQ 620 REEATRLQGE 630 LEKLKKEWDV 640 LENECRSLKK 650 ENVLLSSELQ 660 RQEKELHNSQ 670 KQSLELTSDL 680 SILQMTRKEL 690 ENQMGSLKEQ 700 HLRDEADLKT 710 LLSKAENQAK 720 DVQKEYEKTQ 730 TVLSELKLKF 740 EMTEQEKQSI 750 TDELKQCKDN 760 LKLLREKGNN 770 KPWPWMPMVA 780 ALVAVTAMVL 790 YVPGLARASP

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005813	centrosome
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Cellular Component	GO:0031966	mitochondrial membrane
Cellular Component	GO:0042383	sarcolemma

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.