Search Results
Overview
| Uniprot ID | A0A8I6AXK2 |
|---|---|
| Protein Name | Proton-coupled zinc antiporter SLC30A9, mitochondrial |
| Gene Name | Slc30a9 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 174 | AREKKLRKEAEIEYR |
| 458 | VRAIHDVKATDLGLG |
Function
Mitochondrial proton-coupled zinc ion antiporter mediating the export of zinc from the mitochondria and involved in zinc homeostasis, zinc mobilization as well as mitochondrial morphology and health. In nucleus, functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes
Protein Sequence
10
MFPGLAAAAA
20
AHRCSWAALC
30
RLGGGPAVAR
40
GRSQGWKNLM
50
TFESFTSMIP
60
SIHPQISVLN
70
QVKLYSTNVQ
80
KGGQGSQTPR
90
TDKAPPLTQA
100
VKAVLKKREY
110
GSKYTKNNFI
120
TGVRAINEFC
130
LKSSDLEQLR
140
KIRRRSPHDD
150
TESFTVFLRS
160
DVEAKALEVW
170
GSLEALAREK
180
KLRKEAEIEY
190
RERLFRNQRI
200
LREYGDFLGN
210
TKPRSRAISV
220
FLKGPGKVVM
230
VAICINGLNC
240
FFKFLAWIYT
250
GSASMFSEAI
260
HSLSDTCNQG
270
LLALGISKSV
280
QTPDPSHPYG
290
FSNMRYISSL
300
ISGVGIFMMG
310
AGLSWYHGIM
320
GLLHPQPMES
330
LLWAYCILAG
340
SLVSEGATLL
350
VAINELRRSA
360
QANGTSFYKY
370
VMESRDPSTN
380
VILLEDTAAV
390
LGVMIAATCM
400
GLTSITGNPL
410
YDSLGSLGVG
420
TLLGVVSAFL
430
ISTNIEALLG
440
RSIQPEQVQR
450
LTELLESDPS
460
VRAIHDVKAT
470
DLGLGKVRFK
480
AEVDFDGRVV
490
TRSYLEKQDF
500
DQMMQEIEEV
510
KTPEQLEAFM
520
LKHGENIIDT
530
LGAEVDRLEK
540
ELKKRNPEVR
HVDLEIL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031966 | mitochondrial membrane |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0015297 | antiporter activity |
| Molecular Function | GO:0008324 | monoatomic cation transmembrane transporter activity |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0006829 | zinc ion transport |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.