Search Results

Overview

Uniprot ID	A0A8I6B5U9
Protein Name	Eukaryotic translation initiation factor 3 subunit B
Gene Name	Eif3b
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
240	ADGYKLDKQHTFRVN

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome

Protein Sequence

10 MQDAENVAAP 20 EAAEERAEPA 30 RQQPVSESPP 40 TDEAAGSGGS 50 EVGRTEDAEE 60 DAEARPEPEV 70 RAKPAAQSEE 80 ETAASPAASP 90 TPQSAQEPSA 100 PGKAEAGGEQ 110 ARHPSARAEE 120 EGGSDGSAAE 130 AEPRALENGE 140 ADEPSFSDPE 150 DFVDDVSEEE 160 LLGDVLKDRP 170 QEADGIDSVI 180 VVDNVPQVGP 190 DRLEKLKNVI 200 HKIFSKFGKI 210 INDYYPEEDG 220 KTKGYIFLEY 230 ASPAHAVDAV 240 KNADGYKLDK 250 QHTFRVNLFT 260 DFDKYMTISD 270 EWDIPEKQPF 280 KDLGNLRYWL 290 EEAECRDQYS 300 VIFESGDRTS 310 IFWNDVKDPV 320 SIEERARWTE 330 TYVRWSPKGT 340 YLATFHQRGI 350 ALWGGDKFKQ 360 IQRFSHQGVQ 370 LIDFSPCERY 380 LVTFSPLMDT 390 QDDPQAIIIW 400 DILTGHKKRG 410 FHCESSAHWP 420 IFKWSHDGKF 430 FARMTLDTLS 440 IYETPVSSVF 450 RLSGGLGIED 460 FSWSPGGNII 470 AFWVPEDKDI 480 PARVTLMQLP 490 TRQEIRVRNL 500 FNVVDCKLHW 510 QKNGDYLCVK 520 VDRTPKGTQG 530 VVTNFEIFRM 540 REKQVPVDVV 550 EMKETIIAFA 560 WEPNGSKFAV 570 LHGEAPRISV 580 SFYHVKSNGK 590 IELIKMFDKQ 600 QANTIFWSPQ 610 GQFVVLAGLR 620 SMNGALAFVD 630 TSDCTVMNIA 640 EHYMASDVEW 650 DPTGRYVVTS 660 VSWWSHKVDN 670 AYWLWTFQGR 680 LLQKNNKDRF 690 CQLLWRPRPP 700 TLLSQDQIKQ 710 IKKDLKKYSK 720 IFEQKDRLSQ 730 SKASKELVER 740 RRTMMEDFRQ 750 YRKMAQELYM 760 KQKNERLELR 770 GGVDTDELDS 780 NVDDWEEETI 790 EFFVTEEVIP LGSQE

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0010494	cytoplasmic stress granule
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0016282	eukaryotic 43S preinitiation complex
Cellular Component	GO:0033290	eukaryotic 48S preinitiation complex
Cellular Component	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m
Cellular Component	GO:0045202	synapse
Molecular Function	GO:0003723	RNA binding
Molecular Function	GO:0003743	translation initiation factor activity
Molecular Function	GO:0031369	translation initiation factor binding
Biological Process	GO:0001732	formation of cytoplasmic translation initiation complex
Biological Process	GO:0075522	IRES-dependent viral translational initiation
Biological Process	GO:0006446	regulation of translational initiation
Biological Process	GO:0075525	viral translational termination-reinitiation

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.