Search Results
Overview
| Uniprot ID | A0A8I6GEC9 |
|---|---|
| Protein Name | Elongation factor Ts, mitochondrial |
| Gene Name | Tsfm |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 53 | GYSFVNCKKALETCG |
| 54 | YSFVNCKKALETCGG |
| 64 | ETCGGDLKQAEAWLH |
| 72 | QAEAWLHKQAQKEGW |
| 76 | WLHKQAQKEGWSKAA |
Function
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Participates in mitochondrial translation
Protein Sequence
10
MPTDAPQARA
20
VLLQPSQPWH
30
TLHAGPSLSS
40
SASSKELLMK
50
LRRTTGYSFV
60
NCKKALETCG
70
GDLKQAEAWL
80
HKQAQKEGWS
90
KAAKLHGRKT
100
KEGLIGLLQE
110
ENTAVLVEVN
120
CETDFVSRNV
130
KFQQLVQQVA
140
LGTMAHCQNL
150
TDQLSTYSKG
160
FLNSSELSEL
170
AAGPDGEGSL
180
KDQLALAIGT
190
LGENMSLKRA
200
AWVKVPSGFY
210
VGSYVHGEMQ
220
SPSLQNLVLG
230
KYGALVICQT
240
PEQITNLEEV
250
GRRLGQHVVG
260
MAPLSVGSLD
270
DEPGGETETR
280
MLPQPYLLDP
290
SITLGQYVQP
300
QGVTVVDFVR
310
FECGEGEQVA
EAE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070013 | intracellular organelle lumen |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0003746 | translation elongation factor activity |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.