Search Results
Overview
| Uniprot ID | A0A8I6GKR8 |
|---|---|
| Protein Name | 40S ribosomal protein S12 |
| Gene Name | Rps12l12 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 102 | DREGKPRKVVGCSCV |
Function
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Subunit of the 40S ribosomal complex
Protein Sequence
10
MAEEGIAAGG
20
VMDVNTALQE
30
VLKTALIHDG
40
LVRGIREAAK
50
ALDKRQAHLC
60
VLASNCDEPM
70
YVKLVEALCA
80
EHQINLIKVD
90
DNKKLGEWVG
100
LCKIDREGKP
110
RKVVGCSCVV
120
VKDYGKESQA
130
KDVIEEYFKC
KK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0022627 | cytosolic small ribosomal subunit |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Biological Process | GO:1990145 | maintenance of translational fidelity |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.