Search Results
Overview
| Uniprot ID | A0A8I6GLU8 |
|---|---|
| Protein Name | TAR DNA-binding protein 43 |
| Gene Name | Tardbp |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 84 | YPKDNKRKMDEADAS |
Function
No function data available.
Protein Sequence
10
MSEYIRVTED
20
ENDEPIEIPS
30
EDDGTVLLST
40
VTAQFPGACG
50
LRYRNPVSQC
60
MRGVRLVEGI
70
LHAPDAGWGN
80
LVYVVNYPKD
90
NKRKMDEADA
100
SSAVKVKRAV
110
QKTSDLIVLG
120
LPWKTTEQDL
130
KDYFSTFGEV
140
LMVQVKKDLK
150
TGHSKGFGFV
160
RFTEYETQVK
170
VMSQRHMIDG
180
RWCDCKLPNS
190
KQSPDEPLRS
200
RKVFVGRCTE
210
DMTAEELQQF
220
FCQYGEVVDV
230
FIPKPFRAFA
240
FVTFADDKVA
250
QSLCGEDLII
260
KGISVHISNA
270
EPKHNSNRQL
280
ERSGRFGGNP
290
GGFGNQGGFG
300
NSRGGGAGLG
310
NNQGGNMGGG
320
MNFGAFSINP
330
AMMAAAQAAL
340
QSSWGMMGML
350
ASQQNQSGPS
360
GNNQSQGSMQ
370
REPNQAFGSG
380
NNSYSGSNSG
390
APLGWGSASN
400
AGSGSGFNGG
410
FGSSMDSKSS
GWGM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0035061 | interchromatin granule |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005726 | perichromatin fibrils |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003690 | double-stranded DNA binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0008289 | lipid binding |
| Molecular Function | GO:0140693 | molecular condensate scaffold activity |
| Molecular Function | GO:0003730 | mRNA 3'-UTR binding |
| Molecular Function | GO:0097157 | pre-mRNA intronic binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Biological Process | GO:0061158 | 3'-UTR-mediated mRNA destabilization |
| Biological Process | GO:0070935 | 3'-UTR-mediated mRNA stabilization |
| Biological Process | GO:1990000 | amyloid fibril formation |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0010467 | gene expression |
| Biological Process | GO:0043922 | host-mediated suppression of viral transcription |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0010629 | negative regulation of gene expression |
| Biological Process | GO:0001933 | negative regulation of protein phosphorylation |
| Biological Process | GO:0071765 | nuclear inner membrane organization |
| Biological Process | GO:0032024 | positive regulation of insulin secretion |
| Biological Process | GO:0042307 | positive regulation of protein import into nucleus |
| Biological Process | GO:0042981 | regulation of apoptotic process |
| Biological Process | GO:0051726 | regulation of cell cycle |
| Biological Process | GO:0042752 | regulation of circadian rhythm |
| Biological Process | GO:0010468 | regulation of gene expression |
| Biological Process | GO:0031647 | regulation of protein stability |
| Biological Process | GO:0034976 | response to endoplasmic reticulum stress |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.