Search Results
Overview
| Uniprot ID | A0A8I6GLW2 |
|---|---|
| Protein Name | Citrate synthase |
| Gene Name | Cs |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 375 | KLVAQLYKIVPNILL |
Function
Key enzyme of the Krebs tricarboxylic acid cycle which catalyzes the synthesis of citrate from acetyl coenzyme A and oxaloacetate
Protein Sequence
10
MIPPSKENSS
20
CLVLAARHAS
30
ASSTNLKDIL
40
SNLIPKEQAR
50
VKTFRQQHGK
60
TVVGQITVDM
70
MYGGMRGMKG
80
LVYETSVLDP
90
DEGIRFRGYS
100
IPECQKLLPK
110
AKGGEEPLPE
120
GLFWLLVTGQ
130
MPTEEQVSWL
140
SQEWAKRAAL
150
PSHVVTMLDN
160
FPTNLHPMSQ
170
LSAAITALNS
180
ESNFARAYAE
190
GINRTKYWEL
200
IYEDCMDLIA
210
KLPCVAAKIY
220
RNLYREGSSI
230
GAIDSKLDWS
240
HNFTNMLGYT
250
EPQFTELMRL
260
YLTIHSDHEG
270
GNVSAHTSHL
280
VGSALSDPYL
290
SFAAAMNGLA
300
GPLHGLANQE
310
VLVWLTQLQK
320
EVGKDVSDEK
330
LRDYIWNTLN
340
SGRVVPGYGH
350
AVLRKTDPRY
360
SCQREFALKH
370
LPKDPMFKLV
380
AQLYKIVPNI
390
LLEQGKAKNP
400
WPNVDAHSGV
410
LLQYYGMTEM
420
NYYTVLFGVS
430
RALGVLAQLI
440
WSRALGFPLE
450
RPKSMSTDGL
MKFVDSKSG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Molecular Function | GO:0046912 | acyltransferase activity, acyl groups converted into alkyl on transfer |
| Biological Process | GO:0006101 | citrate metabolic process |
| Biological Process | GO:0006099 | tricarboxylic acid cycle |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.