Search Results
Overview
| Uniprot ID | A0A8J8XU90 |
|---|---|
| Protein Name | Myosin-9 |
| Gene Name | Myh9 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 74 | VNKDDIQKMNPPKFS |
Function
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis. Promotes cell motility in conjunction with S100A4. During cell spreading, plays an important role in cytoskeleton reorganization, focal contact formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10
Protein Sequence
10
MAQQAADKYL
20
YVDKNFINNP
30
LAQADWAAKK
40
LVWVPSTKNG
50
FEPASLKEEV
60
GEEAIVELVE
70
NGKKVKVNKD
80
DIQKMNPPKF
90
SKVEDMAELT
100
CLNEASVLHN
110
LKERYYSGLI
120
YTYSGLFCVV
130
INPYKNLPIY
140
SEEIVDMYKG
150
KKRHEMPPHI
160
YAITDTAYRS
170
MMQDREDQSI
180
LCTGESGAGK
190
TENTKKVIQY
200
LAHVASSHKS
210
KKDQGELERQ
220
LLQANPILEA
230
FGNAKTVKND
240
NSSRFGKFIR
250
INFDVNGYIV
260
GANIETYLLE
270
KSRAIRQAKE
280
ERTFHIFYYL
290
LSGAGEHLKT
300
DLLLEPYNKY
310
RFLSNGHVTI
320
PGQQDKDMFQ
330
ETMEAMRIMG
340
IPEDEQMGLL
350
RVISGVLQLG
360
NIVFKKERNT
370
DQASMPDNTA
380
AQKVSHLLGI
390
NVTDFTRGIL
400
TPRIKVGRDY
410
VQKAQTKEQA
420
DFAIEALAKA
430
TYERMFRWLV
440
LRINKALDKT
450
KRQGASFIGI
460
LDIAGFEIFD
470
LNSFEQLCIN
480
YTNEKLQQLF
490
NHTMFILEQE
500
EYQREGIEWN
510
FIDFGLDLQP
520
CIDLIEKPAG
530
PPGILALLDE
540
ECWFPKATDK
550
SFVEKVVQEQ
560
GTHPKFQKPK
570
QLKDKADFCI
580
IHYAGKVDYK
590
ADEWLMKNMD
600
PLNDNIATLL
610
HQSSDKFVSE
620
LWKDEMQSTQ
630
RAYFYRRFPI
640
LHLESVDRII
650
GLDQVAGMSE
660
TALPGAFKTR
670
KGMFRTVGQL
680
YKEQLAKLMA
690
TLRNTNPNFV
700
RCIIPNHEKK
710
AGKLDPHLVL
720
DQLRCNGVLE
730
GIRICRQGFP
740
NRVVFQEFRQ
750
RYEILTPNSI
760
PKGFMDGKQA
770
CVLMIKALEL
780
DSNLYRIGQS
790
KVFFRAGVLA
800
HLEEERDLKI
810
TDVIIGFQAC
820
CRGYLARKAF
830
AKRQQQLTAM
840
KVLQRNCAAY
850
LRLRNWQWWR
860
LFTKVKPLLN
870
SIRHEDELLA
880
KEAELTKVRE
890
KHLAAENRLT
900
EMETMQSQLM
910
AEKLQLQEQL
920
QAETELCAEA
930
EELRARLTAK
940
KQELEEICHD
950
LEARVEEEEE
960
RCQYLQAEKK
970
KMQQNIQELE
980
EQLEEEESAR
990
QKLQLEKVTT
1000
EAKLKKLEED
1010
QIIMEDQNCK
1020
LAKEKKLLED
1030
RVAEFTTNLM
1040
EEEEKSKSLA
1050
KLKNKHEAMI
1060
TDLEERLRRE
1070
EKQRQELEKT
1080
RRKLEGDSTD
1090
LSDQIAELQA
1100
QIAELKMQLA
1110
KKEEELQAAL
1120
ARVEEEAAQK
1130
NMALKKIREL
1140
ETQISELQED
1150
LESERACRNK
1160
AEKQKRDLGE
1170
ELEALKTELE
1180
DTLDSTAAQQ
1190
ELRSKREQEV
1200
SILKKTLEDE
1210
AKTHEAQIQE
1220
MRQKHSQAVE
1230
ELAEQLEQTK
1240
RVKATLEKAK
1250
QTLENERGEL
1260
ANEVKALLQG
1270
KGDSEHKRKK
1280
VEAQLQELQV
1290
KFSEGERVRT
1300
ELADKVSKLQ
1310
VELDSVTGLL
1320
NQSDSKSSKL
1330
TKDFSALESQ
1340
LQDTQELLQE
1350
ENRQKLSLST
1360
KLKQMEDEKN
1370
SFREQLEEEE
1380
EAKRNLEKQI
1390
ATLHAQVTDM
1400
KKKMEDGVGC
1410
LETAEEAKRR
1420
LQKDLEGLSQ
1430
RLEEKVAAYD
1440
KLEKTKTRLQ
1450
QELDDLLVDL
1460
DHQRQSVSNL
1470
EKKQKKFDQL
1480
LAEEKTISAK
1490
YAEERDRAEA
1500
EAREKETKAL
1510
SLARALEEAM
1520
EQKAELERLN
1530
KQFRTEMEDL
1540
MSSKDDVGKS
1550
VHELEKSKRA
1560
LEQQVEEMKT
1570
QLEELEDELQ
1580
ATEDAKLRLE
1590
VNLQAMKAQF
1600
ERDLQGRDEQ
1610
SEEKKKQLVR
1620
QVREMEAELE
1630
DERKQRSIAM
1640
AARKKLEMDL
1650
KDLEAHIDTA
1660
NKNREEAIKQ
1670
LRKLQAQMKD
1680
CMRELDDTRA
1690
SREEILAQAK
1700
ENEKKLKSME
1710
AEMIQLQEEL
1720
AAAERAKRQA
1730
QQERDELADE
1740
IANSSGKGAL
1750
ALEEKRRLEA
1760
RIAQLEEELE
1770
EEQGNTELIN
1780
DRLKKANLQI
1790
DQINTDLNLE
1800
RSHAQKNENA
1810
RQQLERQNKE
1820
LKAKLQEMES
1830
AVKSKYKASI
1840
AALEAKIAQL
1850
EEQLDNETKE
1860
RQAASKQVRR
1870
AEKKLKDVLL
1880
QVEDERRNAE
1890
QFKDQADKAS
1900
TRLKQLKRQL
1910
EEAEEEAQRA
1920
NASRRKLQRE
1930
LEDATETADA
1940
MNREVSSLKN
1950
KLRRGDMPFV
1960
VTRRIVRKGT
1970
GDCSDEEVDG
1980
KADGADAKAA
E
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0005903 | brush border |
| Cellular Component | GO:0030863 | cortical cytoskeleton |
| Cellular Component | GO:0060473 | cortical granule |
| Cellular Component | GO:0009898 | cytoplasmic side of plasma membrane |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0001772 | immunological synapse |
| Cellular Component | GO:0016460 | myosin II complex |
| Cellular Component | GO:0031594 | neuromuscular junction |
| Cellular Component | GO:0005819 | spindle |
| Cellular Component | GO:0001725 | stress fiber |
| Cellular Component | GO:0001931 | uropod |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Molecular Function | GO:0003774 | cytoskeletal motor activity |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0000902 | cell morphogenesis |
| Biological Process | GO:0060471 | cortical granule exocytosis |
| Biological Process | GO:1903919 | negative regulation of actin filament severing |
| Biological Process | GO:0006911 | phagocytosis, engulfment |
| Biological Process | GO:1903923 | positive regulation of protein processing in phagocytic vesicle |
| Biological Process | GO:0008360 | regulation of cell shape |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.