Search Results
Overview
| Uniprot ID | A0A8L2Q359 |
|---|---|
| Protein Name | 2-iminobutanoate/2-iminopropanoate deaminase |
| Gene Name | Rida |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 168 | YQVAALPKGSRIEIE |
Function
Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex. Acts by bridging YTHDF2 and the ribonuclease P/MRP complex. RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage
Protein Sequence
10
MNYNSHRTLR
20
IHRRRSLNQN
30
SLPRAVWSVT
40
KRVDVVTAVS
50
SLEDLQEGRI
60
SMSSIIRKVI
70
STSKAPAAIG
80
AYSQAVLVDR
90
TIYVSGQIGM
100
DPSSGQLVPG
110
GVAEEAKQAL
120
KNLGEILKAA
130
GCDFTNVVKT
140
TVLLADINDF
150
GTVNEIYKTY
160
FQGNLPARAA
170
YQVAALPKGS
180
RIEIEAIAVQ
GPFTTAGL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Biological Process | GO:0006402 | mRNA catabolic process |
| Biological Process | GO:0061157 | mRNA destabilization |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005777 | peroxisome |
| Molecular Function | GO:0120241 | 2-iminobutanoate/2-iminopropanoate deaminase activity |
| Molecular Function | GO:0003729 | mRNA binding |
| Biological Process | GO:0006629 | lipid metabolic process |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.