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Overview

Uniprot IDA0A8L2Q3U4
Protein NameThy-1 membrane glycoprotein
Gene NameThy1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
121 SLTREKKKHVLSGTL

Function

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain

Protein Sequence

10 MKDIEDSLWF 20 CFPPRGPQAQ 30 IALVVRIEGG 40 GGWQAGGSLR 50 RVTSWLAGCG 60 APQTQDGAIG 70 TMNPVISITL 80 LLSVLQMSRG 90 QRVISLTACL 100 VNQNLRLDCR 110 HENNTNLPIQ 120 HEFSLTREKK 130 KHVLSGTLGV 140 PEHTYRSRVN 150 LFSDRFIKVL 160 TLANFTTKDE 170 GDYMCELRVS 180 GQNPTSSNKT 190 INVIRDKLVK 200 CGGISLLVQN 210 TSWLLLLLLS 220 LSFLQATDFI SL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016324 apical plasma membrane
Cellular Component GO:0009986 cell surface
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0045121 membrane raft
Cellular Component GO:0098552 side of membrane
Molecular Function GO:0005178 integrin binding
Biological Process GO:0034113 heterotypic cell-cell adhesion
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0070571 negative regulation of neuron projection regeneration
Biological Process GO:0002693 positive regulation of cellular extravasation
Biological Process GO:0051894 positive regulation of focal adhesion assembly

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.