Search Results
Overview
| Uniprot ID | A0A8L2QA00 |
|---|---|
| Protein Name | Actin-related protein 2/3 complex subunit 5 |
| Gene Name | Arpc5l |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 69 | RNSPINTKNQAVKER |
Function
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development
Protein Sequence
10
MARNTLSSRF
20
RRVDIDEFDE
30
NKFVDEHEEA
40
AAASGEPGPD
50
PCEVDGLLRQ
60
WDMLRAFHAA
70
LRNSPINTKN
80
QAVKERAQGI
90
VLKVLTNFKS
100
SEIEQAVQSL
110
DRNGIDLLMK
120
YIYKGFEKPT
130
ENSSAVLLQW
140
HEKALAVGGL
150
GSIIRVLTAR
KTV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005885 | Arp2/3 protein complex |
| Molecular Function | GO:0003779 | actin binding |
| Biological Process | GO:0034314 | Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.