Search Results
Overview
| Uniprot ID | A0A8L2QAE6 |
|---|---|
| Protein Name | Adenylyl cyclase-associated protein |
| Gene Name | Cap1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 175 | EYRDVDKKHVDWVRA |
| 276 | KHVSDDMKTHKNPAL |
| 279 | SDDMKTHKNPALKAQ |
| 284 | THKNPALKAQSGPVR |
| 309 | PQTSPSPKPATKKEP |
| 314 | SPKPATKKEPALLEL |
| 324 | ALLELEGKKWRVENQ |
| 363 | TTLQIKGKINSITVD |
| 60 | AEYLKMSKEIGGDVQ |
| 68 | EIGGDVQKHAEMVHT |
| 78 | EMVHTGLKLERALLV |
Function
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity
Protein Sequence
10
MADMQNLVER
20
LERAVGRLEA
30
VSHTSDMHCG
40
YGDSPSKVPY
50
VQAFDSLLAN
60
PVAEYLKMSK
70
EIGGDVQKHA
80
EMVHTGLKLE
90
RALLVTASQC
100
QQPAGNKLSD
110
LLAPISEQIQ
120
EVITFREKNR
130
GSKFFNHLSA
140
VSESIQALGW
150
VALAAKPGPF
160
VKEMNDAAMF
170
YTNRVLKEYR
180
DVDKKHVDWV
190
RAYLSIWTEL
200
QAYIKEFHTT
210
GLAWSKTGPV
220
AKELSGLPSG
230
PSVGSGPPPP
240
PPGPPPPPVP
250
TSSGSDDSAS
260
RSALFAQINQ
270
GESITHALKH
280
VSDDMKTHKN
290
PALKAQSGPV
300
RSGPKPFSAP
310
KPQTSPSPKP
320
ATKKEPALLE
330
LEGKKWRVEN
340
QENVSNLVID
350
DTELKQVAYI
360
YKCVNTTLQI
370
KGKINSITVD
380
NCKKLGLVFD
390
DVVGIVEIIN
400
SRDVKVQVMG
410
KVPTISINKT
420
DGCHAYLSKN
430
SLDCEIVSAK
440
SSEMNVLIPT
450
EGGDFNEFPV
460
PEQFKTLWNG
470
QKLVTTVTEI
AG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030864 | cortical actin cytoskeleton |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0098793 | presynapse |
| Molecular Function | GO:0003779 | actin binding |
| Biological Process | GO:0030036 | actin cytoskeleton organization |
| Biological Process | GO:0098885 | modification of postsynaptic actin cytoskeleton |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.