Search Results
Overview
| Uniprot ID | A0A8L2QBI2 |
|---|---|
| Protein Name | Electron transfer flavoprotein subunit alpha |
| Gene Name | Etfa |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 222 | VSGGRGLKSGENFKL |
| 65 | KVVQDLCKVAGVAKV |
Function
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism
Protein Sequence
10
RRSRQELKQA
20
SLLRFQSTLV
30
IAEHANDSLA
40
PITLNTITAA
50
GRLGGEVSCL
60
VAGTKCDKVV
70
QDLCKVAGVA
80
KVLVAQHDAY
90
KGLLPEELTP
100
LILETQKQFS
110
YTHICAGASA
120
FGKNLLPRVA
130
AKLNVAPVSD
140
IIEIKSPDTF
150
VRTIYAGNAL
160
CTVKCDEKVK
170
VFSVRGTSFE
180
AAAASGGSAS
190
SEKAPSSSSA
200
GISEWLDQKL
210
TKSDRPELTG
220
AKVVVSGGRG
230
LKSGENFKLL
240
YDLADQLHAA
250
VGASRAAVDA
260
GFVPNDMQVG
270
QTGKIVAPEL
280
YIAVGISGAI
290
QHLAGMKDSK
300
TIVAINKDPE
310
APIFQVADYG
320
IVADLFKVVP
EMTEILKKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0045251 | electron transfer flavoprotein complex |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Molecular Function | GO:0009055 | electron transfer activity |
| Molecular Function | GO:0050660 | flavin adenine dinucleotide binding |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.