Search Results
Overview
| Uniprot ID | A0A8L2QDI1 |
|---|---|
| Protein Name | Endoplasmic reticulum chaperone BIP |
| Gene Name | Hspa5 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 155 | AMVLTKMKETAEAYL |
| 164 | TAEAYLGKKVTHAVV |
| 97 | ENTVFDAKRLIGRTW |
Function
No function data available.
Protein Sequence
10
KMKFTVVAAA
20
LLLLCAVRAE
30
EEDKKEDVGT
40
VVGIDLGTTY
50
SCVGVFKNGR
60
VEIIANDQGN
70
RITPSYVAFT
80
PEGERLIGDA
90
AKNQLTSNPE
100
NTVFDAKRLI
110
GRTWNDPSVQ
120
QDIKFLPFKV
130
VEKKTKPYIQ
140
VDIGGGQTKT
150
FAPEEISAMV
160
LTKMKETAEA
170
YLGKKVTHAV
180
VTVPAYFNDA
190
QRQATKDAGT
200
IAGLNVMRII
210
NEPTAAAIAY
220
GLDKREGEKN
230
ILVFDLGGGT
240
FDVSLLTIDN
250
GVFEVVATNG
260
DTHLGGEDFD
270
QRVMEHFIKL
280
YKKKTGKDVR
290
KDNRAVQKLR
300
REVEKAKRAL
310
SSQHQARIEI
320
ESFFEGEDFS
330
ETLTRAKFEE
340
LNMDLFRSTM
350
KPVQKVLEDS
360
DLKKSDIDEI
370
VLVGGSTRIP
380
KIQQLVKEFF
390
NGKEPSRGIN
400
PDEAVAYGAA
410
VQAGVLSGDQ
420
DTGDLVLLDV
430
CPLTLGIETV
440
GGVMTKLIPR
450
NTVVPTKKSQ
460
IFSTASDNQP
470
TVTIKVYEGE
480
RPLTKDNHLL
490
GTFDLTGIPP
500
APRGVPQIEV
510
TFEIDVNGIL
520
RVTAEDKGTG
530
NKNKITITND
540
QNRLTPEEIE
550
RMVNDAEKFA
560
EEDKKLKERI
570
DTRNELESYA
580
YSLKNQIGDK
590
EKLGGKLSPE
600
DKETMEKAVE
610
EKIEWLESHQ
620
DADIEDFKAK
630
KKELEEIVQP
640
IISKLYGSGG
650
PPPTGEEDTS
EKDEL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0008180 | COP9 signalosome |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0034663 | endoplasmic reticulum chaperone complex |
| Cellular Component | GO:0005788 | endoplasmic reticulum lumen |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0051787 | misfolded protein binding |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Molecular Function | GO:0044183 | protein folding chaperone |
| Molecular Function | GO:0140311 | protein sequestering activity |
| Molecular Function | GO:0030291 | protein serine/threonine kinase inhibitor activity |
| Molecular Function | GO:0043022 | ribosome binding |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Biological Process | GO:0042149 | cellular response to glucose starvation |
| Biological Process | GO:0021680 | cerebellar Purkinje cell layer development |
| Biological Process | GO:0021589 | cerebellum structural organization |
| Biological Process | GO:0036498 | IRE1-mediated unfolded protein response |
| Biological Process | GO:0035437 | maintenance of protein localization in endoplasmic reticulum |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:1903898 | negative regulation of PERK-mediated unfolded protein response |
| Biological Process | GO:0030335 | positive regulation of cell migration |
| Biological Process | GO:0031398 | positive regulation of protein ubiquitination |
| Biological Process | GO:0031204 | post-translational protein targeting to membrane, translocation |
| Biological Process | GO:0051603 | proteolysis involved in protein catabolic process |
| Biological Process | GO:1903894 | regulation of IRE1-mediated unfolded protein response |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.