Search Results
Overview
| Uniprot ID | A0A8L2QF19 |
|---|---|
| Protein Name | Protein phosphatase 1 regulatory subunit 14 |
| Gene Name | Ppp1r14a |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | LGKRVLSKLQSPSRA |
Function
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction
Protein Sequence
10
MAAQRLGKRV
20
LSKLQSPSRA
30
RGPGGSPSGL
40
QKRHARVTVK
50
YDRRELQRRL
60
DVEKWIDGRL
70
EELYRGREAD
80
MPDEVNIDEL
90
LELDSEEERC
100
RKIRVGAKER
110
DFVQELLAKL
120
RGLHKQPGFP
130
QPSPSDDPSL
140
SPRQDPAHTA
PP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0004864 | protein phosphatase inhibitor activity |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.