Search Results
Overview
| Uniprot ID | A0A8L2QLE0 |
|---|---|
| Protein Name | Protein FAM162A |
| Gene Name | Fam162a |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 68 | RHRVPLHKPTDFEKK |
Function
Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly
Protein Sequence
10
MTKSTYRSWS
20
GEGKRLGHCF
30
RLCERNVSSP
40
LRLTRNTDLK
50
RINGFCTKPQ
60
ESPKAPTQSY
70
RHRVPLHKPT
80
DFEKKILLWS
90
GRFKKEEEIP
100
ETISFEMLDA
110
AKNKIRVKVS
120
YLMIALTVAG
130
CVYMVIEGKK
140
AAKRHESLTS
150
LNLERKARLR
160
EEAAMKAKAD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.