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Overview

Uniprot IDA0A8L2R7U6
Protein NameProteasome subunit beta
Gene NamePsmb3
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
20 AVMAMKGKNCVAIAA

Function

Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity

Protein Sequence

10 MSFGSVMSYN 20 GGAVMAMKGK 30 NCVAIAADRR 40 FGIQAQMVTT 50 DFQKIFPMGD 60 RLYIGLAGLA 70 TDVQTVAQRL 80 KFRLNLYELK 90 EGRQIKPYTL 100 MSMVANLLYE 110 KRFGPYYTEP 120 VIAGLDPKTF 130 KPFICSLDLI 140 GCPMVTDDFV 150 VSGTCSEQMY 160 GMCESLWEPN 170 MDPEHLFETI 180 SQAMLNAVDR 190 DAVSGMGVIV 200 HIIEKDKITT RTLKARMD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0019774 proteasome core complex, beta-subunit complex
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.