Search Results
Overview
| Uniprot ID | A0A8L2R849 |
|---|---|
| Protein Name | Proteasome subunit beta |
| Gene Name | Psmb7 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 112 | EGMVVADKNCSKIHF |
Function
Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity
Protein Sequence
10
MPNKASSKFA
20
PPFHPVPQLR
30
RKCKFFLVAP
40
PSARKHFLGK
50
MAAVSVFQAP
60
VGGFSFDNCR
70
RNAVLEADFA
80
KKGFKLPKAR
90
KTGTTIAGVV
100
YKDGIVLGAD
110
TRATEGMVVA
120
DKNCSKIHFI
130
SPNIYCCGAG
140
TAADTDMTTQ
150
LISSNLELHS
160
LTTGRLPRVV
170
TANRMLKQML
180
FRYQGYIGAA
190
LVLGGVDVTG
200
PHLYSIYPHG
210
STDKLPYVTM
220
GSGSLAAMAV
230
FEDKFRPDME
240
EEEAKKLVSE
250
AIAAGIFNDL
260
GSGSNIDLCV
270
ISKSKLDFLR
280
PYSVPNKKGT
290
RFGRYRCEKG
300
TTAVLTEKVT
310
PLELEVLEEI
VQTMDTS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0005839 | proteasome core complex |
| Molecular Function | GO:0004298 | threonine-type endopeptidase activity |
| Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0061136 | regulation of proteasomal protein catabolic process |
| Biological Process | GO:0006979 | response to oxidative stress |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.