Overview
| Uniprot ID | A0A8L2R9H0 |
|---|
| Protein Name | 40S ribosomal protein S8 |
|---|
| Gene Name | Rps8 |
|---|
| Organism | Rattus norvegicus |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 129 |
LGRKKGAKLTPEEEE |
Function
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome
Protein Sequence
10
HLGISRDNWH
20
KRRKTGGKRK
30
PYHKKRKYEL
40
GRPAANTKIG
50
PRRIHTVRVR
60
GGNKKYRALR
70
LDVGNFSWGS
80
ECCTRKTRII
90
DVVYNASNNE
100
LVRTKTLVKN
110
CIVLIDSTPY
120
RQWYESHYAL
130
PLGRKKGAKL
140
TPEEEEILNK
150
KRSKKIQKKY
160
DERKKNAKIS
170
SLLEEQFQQG
180
KLLACIASRP
190
GQCGRADGYV
200
LEGKELEFYL
RKIKARKGK
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0022627 |
cytosolic small ribosomal subunit |
| Cellular Component |
GO:0005783 |
endoplasmic reticulum |
| Cellular Component |
GO:0032040 |
small-subunit processome |
| Molecular Function |
GO:0003735 |
structural constituent of ribosome |
| Biological Process |
GO:0042274 |
ribosomal small subunit biogenesis |
| Biological Process |
GO:0006412 |
translation |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.