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Overview

Uniprot IDA0A8L2UIH0
Protein NameCyclin-dependent kinase 5
Gene NameCdk5
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
9 QKYEKLEKIGEGTYG

Function

No function data available.

Protein Sequence

10 MQKYEKLEKI 20 GEGTYGTVFK 30 AKNRETHEIV 40 ALKRVRLDDD 50 DEGVPSSALR 60 EICLLKELKH 70 KNIVRLHDVL 80 HSDKKLTLVF 90 EFCDQDLKKY 100 FDSCNGDLDP 110 EIVKSLLFQL 120 LKGLGFCHSR 130 NVLHRDLKPQ 140 NLLINRNGEL 150 KLADFGLARA 160 FGIPVRCYSA 170 EVVTLWYRPP 180 DVLFGAKLYS 190 TSIDMWSAGC 200 IFAELANAGR 210 PLFPGNDVDD 220 QLKRIFRYPP 230 RTPTEEQWPA 240 MTKLPDYKPY 250 PMYPATTSLV 260 NVVPKLNATG 270 RDLLQNLLKC 280 NPVQRISAEE 290 ALQHPYFSDF CPP

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0030175 filopodium
Cellular Component GO:0030426 growth cone
Cellular Component GO:0030027 lamellipodium
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0043204 perikaryon
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0016533 protein kinase 5 complex
Molecular Function GO:0030549 acetylcholine receptor activator activity
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0005176 ErbB-2 class receptor binding
Molecular Function GO:0043125 ErbB-3 class receptor binding
Molecular Function GO:0051879 Hsp90 protein binding
Molecular Function GO:0035255 ionotropic glutamate receptor binding
Molecular Function GO:0002039 p53 binding
Molecular Function GO:0004674 protein serine/threonine kinase activity
Molecular Function GO:0030547 signaling receptor inhibitor activity
Biological Process GO:0007409 axonogenesis
Biological Process GO:0051301 cell division
Biological Process GO:0051649 establishment of localization in cell
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0045861 negative regulation of proteolysis
Biological Process GO:0051051 negative regulation of transport
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0048709 oligodendrocyte differentiation
Biological Process GO:0017158 regulation of calcium ion-dependent exocytosis
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0061001 regulation of dendritic spine morphogenesis
Biological Process GO:1903076 regulation of protein localization to plasma membrane
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0051966 regulation of synaptic transmission, glutamatergic
Biological Process GO:0007519 skeletal muscle tissue development

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.