Search Results
Overview
| Uniprot ID | A0A8W4F8N1 |
|---|---|
| Protein Name | Transformer-2 protein homolog beta |
| Gene Name | TRA2B |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 97 | RVDFSITKRPHTPTP |
Function
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA
Protein Sequence
10
MSTRRRHVGN
20
RANPDPNCCL
30
GVFGLSLYTT
40
ERDLREVFSK
50
YGPIADVSIV
60
YDQQSRRSRG
70
FAFVYFENVD
80
DAKEAKERAN
90
GMELDGRRIR
100
VDFSITKRPH
110
TPTPGIYMGR
120
PTYGSSRRRD
130
YYDRGYDRGY
140
DDRDYYSRSY
150
RGGGGGGGGW
160
RAAQDRDQIY
170
RRRSPSPYYS
180
RGGYRSRSRS
190
RSYSPRKFLY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.