Search Results

Overview

Uniprot IDA0A8W4F9G7
Protein NameKinesin-like protein
Gene NameKIF23
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
183 REATPNPKTPSSKRQ
628 ETTMKWEKECERRVA
648 MQNKLWVKDEKLKQL
878 EIETKLIKGDVYKTR
883 LIKGDVYKTRGGGQS

Function

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro

Protein Sequence

10 MKPARTKTPR 20 KPPVKKGAQT 30 TLKDPVGVYC 40 RVRPLSLLDQ 50 ECCIEVINNT 60 TVQLHTPEGY 70 RLNRNGDYKE 80 TQYSFKQVFG 90 THTTQKELFD 100 VVANPLVDDL 110 IHGKNGLLFT 120 YGVTGSGKTH 130 TMTGSPGEGG 140 LLPRCLDMIF 150 NSIGSFQAKR 160 YVFKSNDRNS 170 MDIQCEVDAL 180 LERQKREATP 190 NPKTPSSKRQ 200 VDPEFVDMIN 210 VQEFCKAEEV 220 DEDSVYGVFV 230 SYIEIYNNYI 240 YDLLEEVPFD 250 PIKPKPPQSK 260 LLREDKNHNM 270 YVAGCTEVEV 280 KSTEEAFEVF 290 WRGQKKRRIA 300 NTHLNRESSR 310 SHSVFNIKLV 320 QAPLDADGDN 330 VLQEKEQITI 340 SQLSLVDLAG 350 SERTNRTKAE 360 GNRLREAGNI 370 NQSLMTLRTC 380 MEVLRENQMY 390 GTNKMVPYRD 400 SKLTHLFKNY 410 FDGEGKVRMI 420 VCVNPKAEDY 430 EESLQVMRFA 440 EVTQEVEVAR 450 PIDRPICGLT 460 PGRRYRNQAR 470 GGPVGDEPLV 480 SEMVLQSFPP 490 LPPCEILNIN 500 DEQTLPRLIE 510 ALEKRHQLRQ 520 MMTDEFNKQA 530 ITFKALLQEF 540 DNAVLNKENY 550 IQGKLNEKEK 560 VISGQKLEIE 570 RLEKKNKTLE 580 YKIEILEKTT 590 TIYEEDKRSL 600 QQELETQNQK 610 LQRQFSDKRR 620 LEARLQGMMT 630 ETTMKWEKEC 640 ERRVAAKQLE 650 MQNKLWVKDE 660 KLKQLKAIVT 670 EPRTEKPERP 680 SRERDREKVT 690 QRSVSPPPVP 700 LPSNYIAQIS 710 NGQQLMSQPQ 720 LHRRSNSCSS 730 ISVASCISEW 740 EQKIPPYNTP 750 LNVSSIARRR 760 QQEPGQSKTC 770 IVSDRRRGMY 780 WTEGREVVPS 790 FRNEIEIEED 800 HCSRFFFQPD 810 QNAPPIRLRH 820 RRSRSAGDRW 830 VDHKPASNVQ 840 TETVMQPHVP 850 HAITVSVANE 860 KALAKCEKYM 870 LTHQELASDG 880 EIETKLIKGD 890 VYKTRGGGQS 900 VQFTDIETLK 910 QESPTGSRKR 920 RSSTAAPAQP 930 DGTESEWTDV 940 ETRCSVAVEM 950 RAGSQLGPGY 960 QHHAQPKRKK P

Gene Ontology

Classification GO ID Description
Cellular Component GO:0090543 Flemming body
Cellular Component GO:0005874 microtubule
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005819 spindle
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0008017 microtubule binding
Molecular Function GO:0003777 microtubule motor activity
Biological Process GO:0051301 cell division
Biological Process GO:0007018 microtubule-based movement

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.