Search Results
Overview
| Uniprot ID | A0A8W4F9L9 |
|---|---|
| Protein Name | Guanine nucleotide-binding protein-like 3 |
| Gene Name | GNL3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 206 | NWLNYLKKELPTVVF |
| 243 | KTEVCVGKEGLWKLL |
| 450 | ARSIQAIKGPRLAGS |
Function
May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation
Protein Sequence
10
MSLCRLICGN
20
KGLAELKKSS
30
KRMTCHKRYK
40
IQKKVREHHR
50
KLRKEAKKRG
60
RKKPRKDPGI
70
PNSAPFKEAL
80
LREAELRKQR
90
LEELKQQQKL
100
ERQKEQDKKR
110
KLETNPGVEL
120
SHKVLVKEEF
130
GRSKAKKAKS
140
SKQNPKKLYC
150
QELKKVIEAS
160
DVVLEVLDAR
170
DPLGCRCPQV
180
EEAIVKGRQK
190
RLVLVLNKSD
200
LVPTENLENW
210
LNYLKKELPT
220
VVFKASTDLK
230
DKGKRIKERK
240
KVAPFKTEVC
250
VGKEGLWKLL
260
GGFQEIYGKA
270
ICVGVIGFPN
280
VGKSSIINSL
290
KQERICNVGV
300
SMGLTRCMQV
310
VPLDKQITLI
320
DSPGFIASPL
330
NSASALALRS
340
PASIEVIKPM
350
EAASAILSHA
360
DARQVVLKFT
370
VPDFENSLEF
380
FTSFAQRRGL
390
HQKGGSPNVE
400
GAAKLLWSEW
410
TGASLGYYCH
420
PPTSWTLSSH
430
FNESIVTDMK
440
WGFNLEELEK
450
NNARSIQAIK
460
GPRLAGSILF
470
QSSGLTNGII
480
EEGDIPEEPL
490
KQKEQKQEEG
500
EDYGDVDTDQ
510
ESVDKEGDEK
520
SSDTSPAEEA
530
FEAVPKGSQA
540
GEQSALSFVM
550
EKMTEEDDAY
DFSTDYML
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0005730 | nucleolus |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0048027 | mRNA 5'-UTR binding |
| Biological Process | GO:1902895 | positive regulation of miRNA transcription |
| Biological Process | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region |
| Biological Process | GO:0033235 | positive regulation of protein sumoylation |
| Biological Process | GO:0032206 | positive regulation of telomere maintenance |
| Biological Process | GO:0017145 | stem cell division |
| Biological Process | GO:0019827 | stem cell population maintenance |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.